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EFFICACY STUDIES/ SCIENTIFIC ARTICLES
 

Pregnancy and Nutrition

 

Fetal abnormalities can be a result of bad nutrition. Your baby gets all the nutrients required for development in the early years from you. Pre and post natal nutrition play an important role in the composition and function of the brain. Appeton Natal Care C18 is specially formulated to contain 18 types of revelant vitamins and minerals for expecting and nursing mothers.

Larger than usual amount of vitamins as well as minerals are required for the optimum intellectual and physical development during pregnancy and the early stages of life. Thus, it is important to consume vitamin and mineral supplements during pregnancy and breastfeeding.

 

Important facts on pregnancy

 
Pregnancy
Having a baby is exciting yet it can be difficult. Your body undergoes various changes in the 9 months that the baby is within you, including physical and emotional transformation. The foods you eat before and during pregnancy will help prepare your body to support the growth of your baby.

The most favourable time to have a baby is between ages 18 and 35. Your body has completed its own growth and with proper dietary habits is well prepared to nurture a developing baby. Your fertility reduces with time, with an increased risk of a complicated pregnancy and an abnormal baby.

Weight gain
If you are big, your baby will probably be big too, due to the larger placenta. The size of the placenta determines the amount of nutrition available to the fetus, and eventually the birth weight of the neonate. If you are underweight, your baby will be smaller and most likely premature.

The National Academy of Sciences recommends a weight gain of 11-16kg (25-35lb) for women of normal weight, 13-18kg (28-40lb) for underweight women, and 7-11kg (15-25lb) for overweight women. The recommended total weight gain for twin pregnancy is 16-20kg (34-45lb).

Healthy eating
Pregnancy is the time for growth and additional demand for nutrients. You must consume a balanced, nutritious diet and increase your calorie intake to meet the needs of the developing foetus and your changing body. Good nutrition is important even before you know you are pregnant. Sensible eating gives your baby the best chance of a healthy beginning and might even benefit your future health.
 
Nutritional Needs
 

Energy
Additional energy is necessary to support the metabolic demands of pregnancy and foetal growth. The extra calories needed per day in the first trimester are slight. The energy needs increase to about 300 calories per day for the second and third trimester.

It is difficult to specify the exact energy requirements because these vary with pre-pregnancy weight, amount and composition of weight gain, and stage of pregnancy and activity level. It has been suggested that energy needs be evaluated in terms of individual rate of weight gain.

Low calorie intake can result in the breakdown of stored fat in the mother, leading to the production of ketones in her blood and urine. Ketones production is a sign of starvation of a starvation-like state. Extreme level of ketonemia, may be an indicator of maternal malnutrition, with an increased risk of neonatal death.

Protein
You will need more protein throughout pregnancy, beginning early in gestation, due to the increased need. The exact requirements however vary from woman to woman depending on her prepregnancy nutrition, genetic determinants of fetal size and maternal lifestyle behaviour (King 2000; Kalhan 2000). You will probably have no difficulty eating plenty of it, as protein is the least likely nutrient to be lacking in the diet. Protein is needed for the proper development of the foetus and placenta.

Vitamins
Pregnancy doubles a your need for folic acid. Compromise maternal folate intake is associated with several negative pregnancy outcomes including low birth weight, neural tube defects, pre-term labour and spontaneous miscarriage. Folic acid is important in the development of the neural tube of the fetus. The neural tube closes by 28 days of gestation, before most women realize they are pregnant. Therefore, supplementation with folic acid is highly recommended prior to conception and throughout childbearing years (Honein et al. 2001; Scholl & Johnson 2000; Mahan & Escott-Stump 1996). Moreover, folic acid is more bioavailable than food folate (Bailey 2000).

Pregnant women have an increased need for vitamin B 6. Some scientific evidence suggested that moderate doses may reduce emotional symptoms (depression, irritability, tiredness). This B vitamin has also been administered in managing severe nausea and vomiting of pregnancy (Mahan & Escott-Stump 1996).

A study suggested that vitamin A status be improved during pregnancy and lactation as this will influence the composition of breast milk. However, excessive consumption appears to be teratogenic. Inadequate vitamin A during early pregnancy may account for some paediatric congenital abnormalities. Vitamin A deficiency in infants is strongly associated with depressed immune function and higher morbidity and mortality due to infectious diseases (Zile 2001; Azais-Braesco & Pascal 2000; Ortega et al. 1997; Mahan & Escott-Stump 1996).

The amount of vitamin D required is slightly increased. Vitamin D is needed for its positive effects on calcium balance. Vitamin E requirements are believed to increase somewhat during pregnancy, but deficiency in humans is rare and has not been linked with either damage to offspring or reduced fertility. Usual diets provide adequate amounts of vitamin K (Mahan & Escott-Stump 1996).

 

Minerals

 

Approximately 30g of calcium is accumulated during pregnancy, almost all of it in the fetal skeleton (25g). The remainder is stored in the maternal skeleton, presumably in reserve for the calcium demands of lactation (Mahan & Escott-Stump 1996). Several studies revealed a positive association between calcium supplementation and pregnancy-induced hypertension, preeclampsia, maternal health and long-term health benefits for your baby (Prentice 2000; Ritchie & King 2000; Villar& Belizan 2000).

You definitely need extra iron during pregnancy. The increased need is due to the elevated maternal blood supply during pregnancy. Women rarely enter pregnancy with sufficient iron stores to cover all the needs without compromising maternal wellbeing. Maternal anaemia develops in some women who do not use iron supplements. Maternal iron deficiency in pregnancy is associated with preterm delivery and inferior neonatal health (Allen 2000; Mahan & Escott-Stump 1996).

Zinc deficiency might lead to malformation and other poor pregnancy outcomes. Maternal zinc status may also be inversely related to the level of prenatal iron supplementation (Mahan & Escott-Stump 1996). Maternal copper deficiency can lead to various structural and biochemical abnormalities (Keen et al. 1998).

Maternal iodine deficiency has been known to cause cretinism in offspring. Suboptimal iodine nutrition of the mother may also compromise development of her foetus even when cretinism does not occur. Iodine deficiency is now regarded by the WHO as the most preventable cause of brain damage (Hetzel 2000; Mahan & Escott-Stump 1996).

Phosphorus is found in a wide variety of foods and deficiency is rare. The common occurrence of leg cramps at night has been associated to a decline in serum calcium related to a calcium/phosphorus imbalance (Mahan & Escott-Stump 1996).

Pregnancy is a ‘salt-wasting’ condition, where your body can use more salt than usual. The enhanced fluid retention during pregnancy actually increases your body’s demand for sodium. However, moderate intake of salt and other sodium-rich foods is appropriate for everyone (Mahan & Escott-Stump 1996).

 

Pregnancy Don’ts

 

Alcohol
If you are pregnant, the alcohol in your bloodstream is able to pass through the placenta to the baby. A woman who drinks alcohol during pregnancy risks giving birth to an abnormal child with fetal alcohol syndrome (FAS). A child with FAS has a pattern of mental and physical defects. Infants born to mothers who use alcohol during pregnancy experience a higher rate of spontaneous abortion and low-birth-weight delivery (Mahan & Escott-Stump 1996).

Caffeine
Caffeine crosses the placenta and enters the foetus, where it may affect foetal heart rate and breathing. A study indicated that caffeine in just 1 to 3 cups of coffee per day increases the risk of miscarriages. Maternal coffee intake may contribute to maternal and infant anaemia, plus lower birth weight in infants. Caffeine has also been linked to infertility. Caffeine is a diuretic, dehydrating the your body of valuable water and can also be transmitted through breast milk (Cnattingius et al. 2000; Mahan & Escott-Stump 1996).

Smoking
Smoking can cause significant damage to your reproductive system. Nicotine crosses the placenta readily and interferes with oxygen supply to the foetus. Nicotine can also be transmitted through breast milk. Carbon monoxide, another ingredient of tobacco smoke, has been shown to inhibit the release of oxygen into foetal tissues. Smoking during pregnancy increases your risk for miscarriage, premature delivery, low-birth-weight delivery, stillbirth, infant with birth defects and also reduces vitamin E concentration in mature milk. It is never too late to stop smoking, but of course the earlier you stop this habit the better (Glanz 1992; Ortega et al. http://www.cdc.gov/tobacco http://www.lungusa.org/tobacco/smosmpreg.html ).

Numerous factors interact to determine the progress and outcome of pregnancy. It is well accepted your nutritional status affects the outcome of pregnancy. Therefore a balanced and nutritious meal is essential during and prior to pregnancy, to ensure that you get all the required nutrients. This can be done by proper planning of each meals. Supplementation with vitamins and minerals may help too.

 

References:

1.  

Allen, L.H. 2000. Anemia and iron deficiency: effects on pregnancy outcome. Am. J. Clin. Nutr. 71 (5)(suppl): 1280-1284.

2.   Azais-Braesco, V. & Pascal, G. 2000. Vitamin A in pregnancy: requirements and safety limits. Am. J. Clin. Nutr. 71 (5)(suppl): 1325-1333.
3.  

Bailey, L.B. 2000. New standard for dietary folate intake in pregnant women. Am. J. Clin. Nutr. 71 (5)(suppl): 1304-1307.

4.  

Cnattingius, S., Signorello, L.B., Anneren, G., Clausson, B., Ekbom, A., Ljunger, E., Blot, W.J., McLaughlin, J.K., Petterson, G., Rane, A. & Granath, F. 2000. Caffeine intake and the risk of first-trimester spontaneous abortion. New Engl. J. Med. 343 (25): 1839-1845.

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Glanz, S. 1992. Tobacco: Biology & Politics. Waco, TX: Health Edco.

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Hetzel, B.S. 2000. Iodine and neuropsychological development. J. Nutr. 130 (2)(suppl): 493-495.

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HoneinM.A., Paulozzi, L.J., Mathews, T.J., Erickson, J.D., Wong, L.C. 2001. Impact of Folic Acid Fortification of the US Food Supply on the Occurrence of Neural Tube Defects. JAMA. 285:2981-2986.

5.  

Kalhan, S.C. 2000. Protein metabolism in pregnancy. Am. J. Clin. Nutr. 71 (5)(suppl): 1249-1255.

5.  

Keen, C.L., Uriu-Hare, J.Y., Hawk, S.N., Jankowski, M.A., Daston, G.P., Kwik-Uribe, C.L. & Rucker, R.B. 1998. 67 (5): 1003-1011.

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King, J.C. 2000. Physiology of pregnancy and nutrient metabolism. Am. J. Clin. Nutr. 71 (5)(suppl):1218-1225.

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Medicine Digest. 1998. Folate food fortification. 16 (7).

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Ortega, R.M., Andres, P., Martinez, R.M. & Lopez-Solaber, A.M. 1997. Vitamin A status during the third trimester of pregnancy in Spanish women: influence on concentrations of vitamin A in breast milk. Am. J. Clin Nutr. 66 (3): 564-568.

5.  

Ortega, R.M., Lopez-Solaber, A.M., Martinez, R.M., Andres, P. & Quintas, M.E. 1998. Influence of smoking on vitamin E status during the third trimester of pregnancy and on breast-milk tocopherol concentrations in Spanish women. Am. J. Clin. Nutr. 68 (3): 662-667.

5.  

Prentice, A. 2000. Maternal calcium metabolism and bone mineral status. Am. J. Clin. Nutr. 71 (5)(suppl): 1312-1316.

5.  

Ritchie, L.D. & King, J.C. 2000. Dietary calcium and pregnancy-induced hypertension: is there a relation? Am. J. Clin. Nutr. 71 (5)(suppl): 1371-1374.

5.  

Scholl, T. & Johnson, W.G. 2000. Folic acid: influence the outcome of pregnancy. Am. J. Clin. Nutr. 71 (5)(suppl): 1295-1303.

5.  

Villar, J. & Belizan, J.M. 2000. Same nutrient, different hypotheses: disparities in trials of calcium supplementation during pregnancy. Am. J. Clin. Nutr. 71 (5)(suppl): 1375-1379.

5.  

Zile, M.H. 2001. Function of vitamin A in vertebrate embryonic development. J. Nutr. 131 (3): 705-708.

5.  

http://www.cdc.gov/tobacc o

5.  

http://www.lungusa.org/tobacco/smosmpreg.html